High-Volume Solid Dose
Tablets, Capsules & Caplets
Probiotec’s solid dose manufacturing facilities are dedicated to providing your product safely and efficiently to market. A fully functional solid dosage plant with capabilities to manufacture, package, and distribute tablets, capsules and caplets.
SOLID DOSE CAPABILITIES
Our solid dose manufacturing capabilities include:
Probiotec’s high-tech tablet press machines are equipped with an extensive range of tooling, which means that tablets can be made in virtually any shape or size.
Tablets are simple and convenient to use. They provide an accurately measured dosage of the active ingredient in a convenient portable package, and can be designed to protect unstable medications or disguise unpalatable ingredients. Coloured coatings, embossed markings and printing can be used to aid tablet recognition. Manufacturing processes and techniques can provide tablets with special features, such as sustained release or fast dissolving formulations.
Probiotec’s high quality tablet machine tooling facilitates a wide range of tablet diameter and shapes and also ensures tablets are the perfect consistency; strong enough to withstand the stresses of packaging, shipping and handling by pharmacists and patients, yet delicate enough that they disintegrate in the gastric tract.
In the manufacture of pharmaceuticals, encapsulation refers to a range of techniques used to enclose medicines in a relatively stable shell known as a capsule, allowing them to, for example, be taken orally or be used as suppositories.
Probiotec excels in the production of hard-shelled capsules, which are typically made using gelatin and contain dry, powdered ingredients or miniature pellets made by processes of extrusion. Capsules are made in two halves: a lower-diameter “body” that is filled and then sealed using a higher-diameter “cap”.
Since their inception, capsules have been viewed by consumers as the most efficient method of taking medication.
A caplet (“capsule-shaped tablet”) is a smooth, coated, oval-shaped medicinal tablet in the general shape of a capsule. Many caplets have an indentation running down the middle so they may be split in half easier.
In the tablet-pressing process, it is important that all ingredients be fairly dry, powdered or granular, somewhat uniform in particle size, and freely flowing. Our extensive granulation processes are designed to ensure content uniformity of drug or active pharmaceutical ingredients and prevent segregation of mixed particle sized powders.
Active Pharmaceutical Ingredients may be tableted as pure substances, or excipients (binders) and/or disintegrants can be added to formulations to aid in tablet binding and dispersion once swallowed.
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Probiotec is an outstanding source of highly marketable product opportunities for pharmaceutical companies worldwide.
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